Time-lapse video microscopy of an ATRX-depleted HG-shATRX1 cell arrested during mitosis and undergoing mitotic cell death, indicated by the fragmentation and hypercompaction of genomic material.
Time-lapse video microscopy of an ATRX-depleted HG-shATRX1 cell arrested in a prometaphase like state with no evidence of chromosome congression to the metaphase plate.