Selected Publications

Kernohan KD, Jiang Y, Tremblay DC, Bonvissuto AC, Eubanks JH, Mann MR, Bérubé NG. ATRX partners with cohesin and MeCP2 and contributes to developmental silencing of imprinted genes in the brain. Dev Cell. 2010 Feb 16;18(2):191-202.

Solomon LA, Li JR, Bérubé NG, Beier F.Loss of ATRX in chondrocytes has minimal effects on skeletal development. PLoS One. 2009 Sep 23:4(9):e7106.

Medina CF, Mazerolle C, Wang Y, Bérubé NG, Coupland S, Gibbons RJ, Wallace VA, Picketts DJ. Altered visual function and interneuron survival in Atrx knockout mice: Inference for the human syndrome. Hum Mol Genet. 2008 Dec 16.



Seah C, Levy MA (co-first authors), Jiang Y, Mokhtarzada S, Higgs DR, Gibbons RJ, Bérubé NG. Neuronal death resulting from targeted disruption of the Snf2 protein ATRX is mediated by p53. J Neurosci. 2008 Nov 19;28(47):12570-80.

Levy MA, Fernandes AD, Tremblay DC, Seah C, Bérubé NG. The SWI/SNF protein ATRX co-regulates pseudoautosomal genes that have translocated to autosomes in the mouse genome. BMC Genomics. 2008 Oct 8;9:468.

Solomon LA, Bérubé NG, Beier F. Transcriptional regulators of chondrocyte hypertrophy.. Birth Defects Res C Embryo Today. 2008 Jun;84(2):123-30

Ritchie K, Seah C, Moulin J, Isaac C, Dick F, Bérubé NG. Loss of ATRX leads to chromosome cohesion and congression defects. J Cell Biol. 2008 Jan 28;180(2):315-24

Bérubé NG, Healy J, Medina CF, Wu S, Hodgson T, Jagla M, and Picketts DJ. Patient mutations alter ATRX targeting to PML nuclear bodies. Eur J Hum Genet. 2007 Oct 24.



Isaac CE, Francis SM, Martens AL, Julian LM, Seifried LA, Erdmann N, Binné UK, Harrington L, Sicinski P, Bérubé NG, Dyson NJ, and Dick FA. The retinoblastoma protein regulates pericentric heterochromatin. Mol Cell Biol. 2006 May 26(9).

Bérubé NG, Mangelsdorf M, Jagla M, Vanderluit J, Garrick D, Gibbons RJ, Higgs DR, Slack RS, and Picketts DJ. The chromatin-remodeling protein ATRX is critical for neuronal survival during corticogenesis. J Clin Invest. 2005 115, 258-267.

Bérubé NG, Jagla M, Smeenk C, De Repentigny Y, Kothary R, and Picketts DJ. Neurodevelopmental defects resulting from ATRX overexpression in transgenic mice. Hum Mol Genet. 2002 Feb 1;11(3):253-61.

Bérubé NG, Smeenk CA, and Picketts DJ. Cell cycle-dependent phosphorylation of the ATRX protein correlates with changes in nuclear matrix and chromatin association. Hum Mol Genet. 2000 Mar 1;9(4)539-47.

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