An increasing number of proteins have been recently identified as intrinsically disordered (unstructured) yet still biologically functional. Intrinsically disordered proteins (IDPs) perform crucial functions in living cells. Many IDPs are involved in cancer, and other human diseases. To achieve a better understanding of IDPs, we primarily use Nuclear magnetic resonance (NMR) spectroscopy to investigate their structure, dynamics, and interactions with other proteins. This knowledge will improve our understanding of IDPs, and may be useful for developing therapies to treat human diseases. 

 

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