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(Click on a hyperlink to view the abstract from PubMed)

  1. Hughes CS, Postovit LM, Lajoie GA (2010) Matrigel: A Complex Protein Mixture Required for Optimal for Cell Culture Proteomics (in press)

  2. Hughes C, Ma B, Lajoie GA (2009) De novo Sequencing Methods in Proteomics, Methods in Molecular Biology (in press).

  3. Horner MA, Pardee K, Liu S, King-Jones K, Lajoie G, Edwards A, Krause HM, Thummel CS (2009) The Drosophila DHR96 nuclear receptor binds cholesterol and regulates cholesterol homeostasis. Genes Development. 23(23):2711-6.

  4. Cheung J, Beasley FC, Liu S, Lajoie GA, Heinrichs DE. (2009) Molecular characterization of staphyloferrin B biosynthesis in Staphylococcus aureus. Molecular Microbiology 74(3):594-608

  5. Bell AW et al., (2009) A HUPO test sample study reveals common problems in mass spectrometry-based proteomics. Nature Methods (6):423-30.

  6. Ma B, Lajoie G (2009) De Novo Interpretation of Tandem Mass Spectra , Current Protocols in Bioinformatics (in press).

  7. Ho E, Irvine T, Vilk G, Lajoie G, Ravichandran KS, D'Souza SJ, Dagnino L (2009). Integrin-linked kinase interactions with ELMO2 modulate cell polarity. Mol Biol Cell. 20(13):3033-43

  8. Beasley FC, Vinés ED, Grigg JC, Zheng Q, Liu S, Lajoie GA, Murphy ME, Heinrichs DE. Characterization of staphyloferrin A biosynthetic and transport mutants in Staphylococcus aureus. Mol Microbiol. 2009 May;72(4):947-63.

  9. PardeeK , Xu L, Reinking J, Schuetz A, Dong A, Liu S, Zhang R, Tiefenbach J, Lajoie G, Plotnikov AN, Arrowsmith C, Savchenko A, BotchkarevA , Krause HM, Edwards A (2009) The structural basis of gas-responsive transcription by the human nuclear hormone receptor, Rev-erb beta PLoS Biology (in press )

  10. Cahu J, Olichon A, Hentrich C, Schek H, Drinjakovic J, Zhang C, Doherty-Kirby A, Lajoie G, Surrey T. Phosphorylation by Cdk1 increases the binding of Eg5 to microtubules in vitro and in Xenopus egg extract spindles. PLoS ONE. 2008;3(12):e3936. Epub 2008 Dec 15.

  11. Bendall SC, Hughes C, Campbell JL, Stewart MH, Pittock P, Liu S, Bonneil E, Thibault P, Bhatia M, Lajoie GA. An enhanced mass spectrometry approach reveals human embryonic stem cell growth factors in culture. Mol Cell Proteomics. 2008 Oct 20. [Epub ahead of print]

  12. Bendall SC, Booy AT, Lajoie G. Proteomic analysis of pluripotent stem cells. Curr Protoc Stem Cell Biol. 2007 Jul;Chapter 1:Unit 1B.1.

  13. Vilk G, Weber JE, Turowec JP, Duncan JS, Wu C, Derksen DR, Zien P, Sarno S, Donella-Deana A, Lajoie G, Pinna LA, Li SS, Litchfield DW. Protein kinase CK2 catalyzes tyrosine phosphorylation in mammalian cells. Cell Signal. 2008 Nov;20(11):1942-51.

  14. Bendall SC, Hughes C, Stewart MH, Doble B, Bhatia M, Lajoie GA. Prevention of amino acid conversion in SILAC experiments with embryonic stem cells. Mol Cell Proteomics. 2008 May 16.

  15. Zhang Y, Liu S, Lajoie G, Merrill AR. The role of the diphthamide-containing loop within eukaryotic elongation factor 2 in ADP-ribosylation by Pseudomonas aeruginosa exotoxin A. Biochem J. 2008 Jul 1;413(1):163-74.

  16. Shan B, Ma B, Zhang K, Lajoie G. Complexities and algorithms for glycan sequencing using tandem mass spectrometry. J Bioinform Comput Biol. 2008 Feb;6(1):77-91.

  17. Liu S, Zhao L, Manzanares D, Doherty-Kirby A, Zhang C, Possmayer F, Lajoie GA. (2008) Characterization of bovine surfactant proteins B and C by electrospray ionization mass spectrometry. Rapid Commun Mass Spectrom. 22(2):197-203.

  18. Grohe B, O'Young J, Ionescu DA, Lajoie GA, Rogers KA, Karttunen M, Goldberg HA, Hunter GK. (2007) Control of calcium oxalate crystal growth by face-specific adsorption of an osteopontin phosphopeptide. J Am Chem Soc. 129(48):14946-51.

  19. Bendall SC, Stewart MH, Menendez P, George D, Vijayaragavan K, Werbowetski-Ogilvie T, Ramos-Mejia V, Rouleau A, Yang J, Bossé M, Lajoie GA, Bhatia M. (2007) IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro. Nature. 448(7157):1015-21.

  20. Manzanares D, Rodriguez-Capote K, Liu S, Haines T, Ramos Y, Zhao L, Doherty-Kirby A, Lajoie GA, Possmayer F. Modification of tryptophan and methionine residues is implicated in the oxidative inactivation of surfactant protein B.Biochemistry 2007 46(18):5604-15.

  21. Ballard, J.N.M.; Lajoie, G.A.; Yeung, K. K.-C. Selective sampling of multiply phosphorylated peptides by capillary electrophoresis for electrospray ionization mass spectrometry analysis. J. Chromatogr. A (In press)

  22. Zhang, H.; Hunter, G.K.; Goldberg, H.A.; Lajoie, G.A.; Yeung, K. K.-C. An integrated procedure of selective injection, sample stacking and fractionation of phosphopeptides for MALDI MS analysis. Anal. Chim. Acta 2007, 581, 268-280.

  23. Ferguson, P. L.; Pan, J.; Wilson, D. J.; Dempsey, B.; Lajoie, G.; Shilton, B.; Konermann, L. Hydrogen/deuterium scrambling during quadrupole time-of-flight MS/MS analysis of a zinc-binding protein domain. Anal. Chem. 2007, 79, 153-160.

  24. Rintala-Dempsey, A.C.; Santamaria-Kisiel, L.; Liao, Y.; Lajoie, G.; Shaw, G.S. Insights into S100 target specificity examined by a new interaction between S100A11 and Annexin A2. Biochemistry 2006, 45, 14695-14705.

  25. Liu, S.; Zhang, C.; Campbell, J.L.; Zhang, H.; Yeung, K. K.-C.; Han, V.K.M.; Lajoie, G.A. Formation of phosphopeptide-metal ion complexes in liquid chromatography/electrospray mass spectrometry and their influence on phosphopeptide detection. Rapid Commun. Mass Spectrom. 2005, 19, 2747-2756.

  26. Reinking J. Lam, M.M.; Pardee, K.; Sampson, H.M.; Liu, S.; Yang, P.; Williams, S.;White, W.; Lajoie, G.; Edwards, A.; Krause, H.M. The Drosophila nuclear receptor e75 contains heme and is gas responsive. Cell 2005, 122, 195-207.

  27. Zhang, H.; Zhang, C.; Lajoie, G.A.;  Yeung, K. K.-C. Selective sampling of phosphopeptides for detection by MALDI mass spectrometry. Anal. Chem. 2005, 77, 6078-6084.

  28. Canton, D. A.; Olsten, M.K.; Kim, K.; Doherty-Kirby, A.; Lajoie, G.; Cooper, J.A.; Litchfield, D.W. The Pleckstrin homology domain-containing protein CKIP-1 is involved in regulation of cell morphology, the actin cytoskeleton and interactions with actin capping proteins.Mol. Cell. Biol. 2005, 25, 3519-3534.

  29. Keykhosravani, M.;  Doherty-Kirby, A.; Zhang, C.;  Goldberg, A.; Hunter, G.K.; Lajoie, G.  Comprehensive identification of posttranslational modifications in rat bone osteopontin by mass spectrometry. Biochemistry 2005, 44, 6990-7003.

  30. Kim, A.R.; Doherty-Kirby, A.; Lajoie, G.; Rylett, R.J; Shilton, B.H. Two methods for large-scale purification of recombinant human choline acetyltransferase. Protein Expr. Purif. 2005, 40, 107-117.

  31. Buscemi, N.; Murray, C.; Doherty-Kirby, A.; Lajoie, G.; Sussman, M.A.; Van Eyk, J.E.  Myocardial subproteomic analysis of a constitutively active Rac1-expressing transgenic mouse with lethal myocardial hypertrophy. Am. J. Physiol. Heart Circ. Physiol. 2005, 289, H2325-2333.

  32. Perdicakis, B.; Montgomery, H.J.; Abbott, G.L.; Fishlock, D.; Lajoie, G.A.; Guillemette, J.G.; Jervis, E.  Photocontrol of nitric oxide production in cell culture using a caged isoform selective inhibitor. Bioorg. Med. Chem. 2005, 13, 47-57.

  33. Simmons, D.A.; Wilson, D.J.; Lajoie, G.A.; Doherty-Kirby, A.; Konermann, L. Subunit disassembly and unfolding of hemoglobin studied by time-resolved electrospray mass spectrometry. Biochemistry 2004, 43, 14792-14801.

  34. Dempsey, B.R.; Wrona, M.; Moulin, J.M.; Gloor, G.B.; Jalilehvand, F.; Lajoie, G.; Shaw, G.S.; Shilton, B.H.  Solution NMR structure and X-ray absorption analysis of the C-terminal zinc-binding domain of the SecA ATPase. Biochemistry 2004, 43, 9361-71.

  35. Dobransky, T.; Doherty-Kirby, A.; Kim, A.R.; Brewer, D.; Lajoie, G.; Rylett, R.J.  Protein kinase C isoforms differentially phosphorylate human choline acetyltransferase regulating its catalytic activity. J. Biol. Chem. 2004, 279, 52059-52068.

  36. Pampena, D. A.; Robertson, K. A.; Litvinova, O.; Lajoie, G.; Goldberg, H. A.; Hunter, G. K. Inhibition of hydroxyapatite formation by osteopontin phosphopeptides. Biochem. J. 2004, 378, 1-5.

  37. Zhang, C.; Doherty-Kirby, A.; van Huystee, R.; Lajoie, G. Investigation of cationic peanut peroxidase glycans by electrospray ionization mass spectrometry.  Phytochemistry 2004, 65, 1575-1588.

  38. Dale, S. E.; Doherty-Kirby, A.; Lajoie, G.; Heinrichs, D. E. Role of siderophore biosynthesis in the virulence of Staphylococcus aureus: Identification and characterization of genes involved in the production of a siderophore. Infect. Immun. 2004, 72, 29-37.

  39. Ma, B.; Zhang, K.; Hendrie, C.; Liang, C.; Li, M.; Doherty-Kirby, A.; Lajoie, G. PEAKS: powerful software for peptide de novo sequencing by tandem mass spectrometry. Rapid Commun. Mass Spectrom. 2003, 17, 2337-2342.

  40. Graham, L.A.; Brewer, D.; Lajoie, G.; Davies, P.L. Characterization of a subfamily of beetle odorant-binding proteins found in hemolymph.  Mol. Cell. Proteomics 2003, 2, 541-549.

  41. Buscemi, N.; Doherty-Kirby, A.; Sussman, M. A.; Lajoie, G.; Van Eyk, J. E. Proteomic analysis of Rac1 transgenic mice displaying dilated cardiomyopathy reveals an increase in creatine kinase M-chain protein abundance. Mol. Cell. Biochem. 2003,251, 145-151.

  42. Sanishvili, R.; Yakunin, A. F.; Laskowski, R. A.; Skarina, T.; Evodokimova, E.; Doherty-Kirby, A.; Lajoie, G. A.; Thornton, J. M.; Arrowsmith, C. H.; Savchenko, A.; Joachimiak, A.; Edwards, A.M. Integrating structure, bioinformatics and enzymology to discover function: BioH, a new carboxylesterase from Escherichia coli. J. Biol. Chem. 2003, 278, 26039-26045.

  43. Donella-Deana, A.; Cesaro, L.; Sarno, S.; Ruzzene, M.; Brunati, A.M.; Marin, O.; Vilk, G.; Doherty-Kirby, A.; Lajoie, G.; Litchfield, D.W.; Pinna, L.A. Tyrosine phosphorylation of protein kinase CK2 by Src-related tyrosine kinases correlates with increased catalytic activity. Biochem. J. 2003, 372, 841-849.

  44. Dobransky T.; Brewer D.; Lajoie G. A.; Rylett R. J. Phosphorylation of 69 kDa choline acetyltransferase at threonine-456 in response to short-term exposure to amyloid-beta peptide 1-42. J. Biol. Chem. 2003, 278, 5883-5893.

  45. Buscemi N.; Doherty-Kirby A.; Sussman M.; Lajoie G.; Van Eyk J.E. Proteomics analysis of RAc1 transgenic mice displaying cardiomyopathy reveals an increase in creatine kinase M-chain abundance. Mol. Cell. Biochem. 2002, 251, 145-151.

  46. Siemann S.; Brewer D.; Clarke A.J.; Dmitrienko G.; Lajoie G.; Viswanatha T. IMP-1 metallo-beta-lactamase: effect of chelators and assessment of metal requirement by electrospray mass spectrometry. Biochim. Biophys. Acta 2002, 1571, 190-200.

  47. Brewer D.; Lajoie G. Structure-based design of potent histatin analogues. Biochemistry 2002, 41, 5526-5536.

  48. Montgomery H.J.; Perdicakis B.; Fishlock D.; Lajoie G.A.; Jervis E.; Guy Guillemette J. Photo-control of nitric oxide synthase activity using a caged isoform specific inhibitor. Bioorg. Med. Chem. 2002, 10,1919-1927.

  49. Fishlock, D.; Guillemette, J. G.; Lajoie G. A. Synthesis of syn and anti isomers of trans-cyclopropyl arginine. ;J. Org. Chem. 2002,67, 2352-2354.

  50. Doherty-Kirby, A.L.; Lajoie, G.A. Investigation of calcium-binding proteins using electrospray ionization mass spectrometry. Methods Mol. Biol. 2002, 173, 161-174.

  51. Rose, N.G.W.; Blaskovich, M.A.; Wong, A.; Lajoie, G. Synthesis of enantiomerically enriched b-g-didehydro amino acids. Tetrahedron 2001, 57, 1497-1507.

  52. Yeh, S.; Moffatt, B.A.; Griffith, M.; Xiong, F.; Yang, D.S.; Wiseman, S.B.; Sarhan, F.; Danyluk, J.; Xue, Y.Q.; Hew, C.L.; Doherty-Kirby, A.; Lajoie, G.  Chitinase genes responsive to cold encode antifreeze proteins in winter cereals. Plant Physiol. 2000, 124, 1251-1264.

  53. Brewer, D.; Lajoie, G. Evaluation of the metal binding properties of the histidine-rich antimicrobial peptides histatin 3 and 5 by electrospray ionization mass spectrometry. Rapid Commun. Mass Spectrom. 2000, 14, 1736-1745.


Presentations in Conference Proceedings

(Click on a hyperlink to view the poster or abstract)

2006
Bendall, S.C.; Stewart, M.; George, D.; Pittock, P.; Li, L.; Campbell, J.L.; Bhatia, M.; Lajoie, G.  The protein microenvironment of human embryonic stem cells: a comprehensive mass spectrometry-based proteomic approach.  Oral presentation at the 19th Lake Louise Workshop on Tandem Mass Spectrometry, Lake Louise, AB, November-December 2006.
Campbell, J.L., Bendall, S.C.; Ye, Z.; Pittock, P.P.; Yin, H.; Brennen, R.; Killeen, K.; Lajoie, G.A.  Combining microfluidic HPLC chip technology with a hybrid triple quadrupole FT-ICR mass spectrometer for novel “bottom-up” and “top-down” protein analyses.   Poster presentation at the 19th Lake Louise Workshop on Tandem Mass Spectrometry, Lake Louise, AB, November-December 2006.
Ballard, J.N.M.; Rustomji, K.; Zhang, H.; Bendall, S.C.; Pittock, P.P.; Lajoie, G.A.; Yeung, K.K.-C.  Selective injection and fractionation of phosphopeptides by capillary electrophoresis for MALDI and ESI mass spectrometry.  Poster presentation at 30th International Symposium & Exhibit on High Performance Liquid Phase Separations and Related Techniques.  (HPLC 2006), San Francisco, CA, June 2006.
Campbell, J.L.; Pittock, P.P.; Bendall, S.; Yin, H.; Brennen, R.; Killeen, K.; Lajoie, G.A.  Combining microfluidic HPLC chip technology with a hybrid triple quadrupole Fourier transform ion cyclotron resonance mass spectrometer (QFT-12).  Poster presentation at the 54th Annual Meeting of the American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics, Seattle, WA, June 2006.
Ma, B.; Lajoie, G.  Improved positional confidence score in de novo sequencing by tandem mass spectrometry.  Poster presentation at the 54th Annual Meeting of the American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics, Seattle, WA, June 2006.
Zhang, C.; Liu, S.; Lenehan, J.; Litchfield, D.W.; Lajoie, G.A. Global phosphoproteome analysis by combining highly selective TiO2 enrichment and EDTA-enhanced detection by LC-MS.  Poster presentation at the 54th Annual Meeting of the American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics, Seattle, WA, June 2006.
Yang, W.; Chen, W.; Rogers, I.; Bendall, S.; Smith, D.; Ma, B.; Lajoie, G.  PEAKS-Q: Software for MS-based quantitative proteomics. Poster presentation at the 54th Annual Meeting of the American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics, Seattle, WA, June 2006.
2005
Yang, W.; Zhang, C.; Ma, B.; Lajoie, G. Software for protein identification by MALDI-TOF MS of microwave-assisted acid hydrolyzed proteins.  Poster presentation at the 53rd Annual Meeting of the American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics, San Antonio, TX, June 2005.
Zhang, C.; Doherty-Kirby, A.; Kahn, M.; Emani, K.; Lajoie, G.  A case study: Identification of three phosphorylation sites of adenoviral E1A-binding protein (p300) by LC-ESI-MS/MS.  Poster presentation at the 53rd Annual Meeting of the American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics, San Antonio, TX, June 2005.
Ma, B.; Lajoie, G.  Improving the de novo sequencing accuracy by combining two independent scoring functions in PEAKS software.  Poster presentation at the 53rd Annual Meeting of the American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics, San Antonio, TX, June 2005.
Bendall, S.C.; Rouleau, A.; Gallacher, L.; George, D.; Bhatia, M.; Lajoie, G.  Profile of secreted proteins in conditioned media which supports the prolonged growth of human embryonic stem cells (hESC).  Poster presentation at the 53rd Annual Meeting of the American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics, San Antonio, TX, June 2005.
Liu, S.; Manzanares, D.; Doherty-Kirby, A.; Possmayer, F.; Lajoie, G.A.  Mass spectrometric analysis of surfactant proteins.  Poster presentation at the 53rd Annual Meeting of the American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics, San Antonio, TX, June 2005.
Campbell, J.L.; Zhang, C.; Yang, W.; Ma, B.; Lajoie, G.A. Analysis of polypeptide ladders produced by microwave-induced acid hydrolysis of proteins with atmospheric pressure matrix-assisted laser desorption/ionization–triple quadrupole Fourier transform ion cyclotron resonance mass spectrometry (AP-MALDI-QFT).  Poster presentation at the 53rd Annual Meeting of the American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics, San Antonio, TX, June 2005.
Booy, A.T. ; Pittock, P.P.; Campbell, J.L.; Han, V.; Lajoie, G.A.  Establishment of the full term placental chorionic villous proteome by free flow electrophoresis and 2D SDS PAGE.  Poster presentation at the 53rd Annual Meeting of the American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics, San Antonio, TX, June 2005.
Zhang, H.; Zhang, C.; Lajoie, G.A.; Yeung, K.K.-C.  Selective sampling of phosphopeptides based on isoelectric point (pI) for ultra-sensitive MALDI MS analysis.  Poster presentation at the 53rd Annual Meeting of the American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics, San Antonio, TX, June 2005.
Ballard, J.N.M.; Zhang, H.; Zhang, C.; Yeung, K.K.-C.; Lajoie, G.A.  Sensitive phosphopeptide analysis: selective extraction and injection of phosphopeptides using capillary electrophoresis (CE) coupled ESI-MS.  Poster presentation at the 53rd Annual Meeting of the American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics, San Antonio, TX, June 2005.
2004
Vilk, G.J.A.; Lajoie, G.  Delineating the signaling pathway of Histatin H5 in yeast.  Poster presentation at the 52nd Annual Meeting of the American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics, Nashville, TN, May 2004.
Bendall, S.C.; Pittock, P.; Bhatia, M.; Lajoie; G.  A proteomic strategy to analyze secreted factors from cell culture. Poster presentation at the 52nd Annual Meeting of the American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics, Nashville, TN, May 2004.
Shan, B.; Zhang, K.; Ma, B.; Zhang, C.; Lajoie, G.  GlycoMaster - A software for interpretation of glycopeptides from MS/MS spectra. Poster presentation at the 52nd Annual Meeting of the American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics, Nashville, TN, May 2004.
Ma, B.; Doherty-Kirby, A.; Booy, A.; Olafson, B.; Lajoie, G.  A comprehensive comparison of the de novo sequencing accuracies of PEAKS, BioAnalyst and PLGS.  Poster presentation at the 52nd Annual Meeting of the American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics, Nashville, TN, May 2004.
Zhang, C.; Doherty-Kirby, A.; van Huystee, R.; Lajoie, G.   Investigation of cationic peanut peroxidase glycans by electrospray ionization mass spectrometry.  Poster presentation at the 52nd Annual Meeting of the American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics, Nashville, TN, May 2004.
Zhang, H.; Zhang, K.; Ma, B.; Zhang, C.; Doherty-Kirby, A.; Lajoie, G.  FOOTPRINT: A New Algorithm for Charge State Deconvolution of Complex ESI Mass Spectra.  Poster presentation at the 52nd Annual Meeting of the American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics, Nashville, TN, May 2004.
Doherty-Kirby, A.; Zhang, C.; Keykhosravani, M.; Brewer, D.; Goldberg, H.; Hunter, G.K.; Lajoie, G.  Post-translational modification analysis of native rat bone osteopontin.  Poster presentation at the 52nd Annual Meeting of the American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics, Nashville, TN, May 2004.
2003
Keykhosravani, M.; Doherty-Kirby, A.; Vilk, G.; Goldberg, H.; Hunter, G.K.; Lajoie, G.  Localization of phosphorylated residues in rat bone osteopontin. Proceedings of the 51st ASMS Conference on Mass Spectrometry and Allied Topics, Montreal, PQ, June 2003.
Doherty-Kirby, A. L.; Guillemette, J.G.; Lajoie, G.A.  Gas phase stability of protein-protein complexes.  Proceedings of the 51st ASMS Conference on Mass Spectrometry and Allied Topics, Montreal, PQ, June 2003.
Heidelberger, S.; Lajoie, G.  Determination of potential protein binding targets of histatin 5 in Saccharomyces cerevisiae.  Proceedings of the 51st ASMS Conference on Mass Spectrometry and Allied Topics, Montreal, PQ, June 2003.
Simmons, D.A.; Dunn, S.D.; Doherty-Kirby, A.; Lajoie, G.; Konermann, L.  Myoglobin conformational dynamics studied by ESI-MS and H/D exchange. Proceedings of the 51st ASMS Conference on Mass Spectrometry and Allied Topics, Montreal, PQ, June 2003.
Zhang, C.; Doherty-Kirby, A.; van Huystee, R.B.; Lajoie, G.  Characterization of the N-linked glycans of cationic peanut peroxidase. Proteome Society Meeting, Toronto, ON, November, 2003.
Dobransky, T.; Doherty-Kirby, A.; Brewer, D.; Lajoie, G.; Rylett, R.J.  Identification of protein kinase-C isoform-specific phosphorylation sites of human choline acetyltransferase by mass spectrometry.  HUPO 2nd Annual & IUBMB XIX Joint World Congress, Montreal, QC, October 2003.
Doherty-Kirby, A.;  Keykhosravani, M.; Brewer, D.; Zhang, C.; Goldberg, H.; Hunter, G.K.; Lajoie, G.  Post-translational modification analysis of native rat bone osteopontin.  HUPO 2nd Annual & IUBMB XIX Joint World Congress, Montreal, QC, October 2003. 
Gupta, M.; Liu, S.; Doherty-Kirby, A.; Lajoie, G.; Gratton, R.; Tardieu, D.; Han, V.  Pathophysiology of intrauterine growth restriction (IUGR): a proteomics approach. HUPO 2nd Annual & IUBMB XIX Joint World Congress, Montreal, QC, October 2003.
Kim, A. Doherty-Kirby, A.; Rylett, R.J.; Shilton, B.H.  Post-translational modification analysis of choline acetyltransferase. HUPO 2nd Annual & IUBMB XIX Joint World Congress, Montreal, QC, October 2003.
Arrell, D.K.; Elliot, S.T.; Murata, M.; Brown, H.A.; Doherty-Kirby, A.; Lajoie, G.A.; Marban, E.; Van Eyk, J. E.  Functional mechanistic convergence of the preconditioning agents adenosine and diazoxide at the level of oxidative metabolism. Scientific Conference on Molecular Mechanisms of Growth, Death, and Regeneration in the Myocardium: Basic Biology and Insights Into Ischemic Heart Disease and Heart Failure, Snowbird, Utah, August 2003.
Lajoie, G.  Protein kinase CK2 catalyses tyrosine phosphorylation in mammalian cells. The 3rd International Conference of the Canadian Proteomics Initiative, Vancouver, BC. May 2003.
2002
Doherty-Kirby, A.L.; Lajoie, G.A.  ESI-MS of serine protease-inhibitor complexes: A site-directed mutagenesis study.  Proceedings of the 50th ASMS Conference on Mass Spectrometry and Allied Topics, Orlando, FL, June 2002.
Ma, B.; Zhang, K.; Lajoie, G.; Doherty-Kirby, A.; Liang, C.; Li, M.  PEAKS: A powerful software tool for the de novo sequencing of peptides from MS/MS data.  Proceedings of the 50th ASMS Conference on Mass Spectrometry and Allied Topics, Orlando, FL, June 2002.
Brewer, D.; Graham, L.: Davies, P.; Lajoie, G.  Identification of novel odorant binding proteins in the beetle Tenebrio, molitor.  Proceedings of the 50th ASMS Conference on Mass Spectrometry and Allied Topics, Orlando, FL, June 2002.
 

Papers that have acknowledged BMSL

 

Vijayakumar, S.; Merkx-Jacques, A.; Ratnayake, D.B.; Gryski, I.; Obhi, R.K.; Houle, S.; Dozois, C.M.; Creuzenet, C.  Cj1121c, a novel UDP-4-keto-6-deoxy-GlcNAc C-4 aminotransferase essential for protein glycosylation and virulence in Campylobacter jejuni.  J. Biol. Chem. 2006, 281, 27733-27743.
 

Briere, L.-A. K.; Dunn, S.D.  The periplasmic domains of Escherichia coli HflKC oligomerize through right-handed coiled-coil interactions.  Biochemistry 2006, 45, 8607-8616.
 

Del Rizzo, P.A.; Bi, Y.; Dunn, S.D.  ATP synthase b subunit dimerization domain: a right-handed coiled coil with offset helices.  J. Mol. Biol. 2006, 364,735-746
 

Cipriano, D.J.; Wood, K.S.; Bi, Y.; Dunn, S.D.  Mutations in the dimerization domain of the b subunit from the Escherichia coli ATP synthase.  Deletions disrupt function but not enzyme assembly.  J. Biol. Chem. 2006, 281, 12408-12413.

 

Laughton, J.M.; Devillard, E.; Heinrichs, D.E.; Reid, G.; McCormick, J.K.  Inhibition of expression of a staphylococcal superantigen-like protein by a soluble factor from Lactobacillus reuteri.  Microbiology 2006, 152, 1155-1167.

 

Dale, S.E.; Sebulsky, M.T.; Heinrichs, D.E.  Involvement of SirABC in iron-siderophore import in Staphylococcus aureus.  J. Bacteriol. 2004, 186, 8356-8362.
 

Kim, A.-R.;  Rylett, R.J.; Shilton, B.H. Substrate binding and catalytic mechanism of human choline acetyltransferase.  Biochemistry 2006, 45, 14621-14631.
 

Obhi, R.K.; Creuzenet, C. Biochemical characterization of the Campylobacter jejuni Cj1294, a novel UDP-4-keto-6-deoxy-GlcNAc aminotransferase that generates UDP-4-amino-4,6-dideoxy-GalNAc.  J. Biol. Chem. 2005, 280, 20902-20908.
 

Tye, C.E.; Hunter, G.K.; Goldberg, H.A.  Identification of the type I collagen-binding domain of bone sialoprotein and characterization of the mechanism of interaction.  J. Biol. Chem. 2005, 280, 13487-13492.
 

Merkx-Jacques, A.; Obhi, R.K.; Bethune, G.; Creuzenet, C.  The Helicobacter pylori flaA1 and wbpB genes control lipopolysaccharide and flagellum synthesis and function.  J. Bacteriol. 2004, 186, 2253-2265.
 

Creuzenet, C. Characterization of CJ1293, a new UDP-GlcNAc C6-dehydratase from Campylobacter jejuni.  FEBS Letters 2004, 559, 136-140.

 

Mack, J.; Vermeiren, C.; Heinrichs, D.E.; Stillman, M.J.  In vivo heme scavenging by Staphylococcus aureus IsdC and IsdE proteins.  Biochem. Biophys. Res. Commun. 2004, 320, 781-788.
 

Del Rizzo, P.A.; Bi, Y.; Dunn, S.D.; Shilton, B.H.  The "second stalk" of Escherichia coli ATP synthase: Structure of the isolated dimerization domain.  Biochemistry 2002, 41, 6875-6884.
 

Ferguson, P. L.; Shaw, G. S.  Role of the N-terminal helix I for dimerization and stability of the calcium-binding protein S100B.  Biochemistry 2002, 41, 3637-3646.
 

Sharpe, S.; Barber K.R.; Grant, C.W.   Interaction between ErbB-1 and ErbB-2 transmembrane domains in bilayer membranes. FEBS Lett. 2002, 519, 103-107.
 

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Last modified on November 7, 2008 by Jonathan Meyer